The original motion picture score for "There Will Be Blood" was composed by Jonny Greenwood, the guitarist of Radiohead. The soundtrack is known for its haunting and atmospheric qualities, featuring a blend of contemporary classical and avant-garde elements. Greenwood's compositions create a sense of tension and unease, perfectly complementing the film's themes of greed, ambition, and isolation. The score includes tracks like "Open Spaces," "Future Markets," and the iconic "There Will Be Blood," which has become synonymous with the film's most intense moments.

The score was widely acclaimed and received several nominations, including a Grammy Award for Best Score Soundtrack Album for Motion Picture, Television, or Other Visual Media. Although it was ruled ineligible for an Academy Award due to the use of pre-existing material, it remains one of the most memorable and influential film scores of the 21st century.

Greenwood's work on "There Will Be Blood" is often praised for its ability to evoke the film's dark and brooding atmosphere, making it an essential component of the movie's success.